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Relationship Between Serum Hepcidin and Ferritin Levels in Patients With Thalassemia Major and Intermedia in Southern Iran
Hepcidin Hydroxyurea Ferritin Thalassemia Intermedia Thalassemia Major
2015/11/9
Background: Hepcidin is a key regulator of iron absorption in humans. It is mainly affected by hypoxia and iron stores.
A Study on Proteolytic Enzyme Activity in the Erythrocytes of Diabetic Patients
Oxidative stress Proteolytic activity Diabetes mellitus
2015/7/21
The present study demonstrates the possibility of increased proteolytic activities in diabetic individuals. Proteolytic activity was measured by the amount of amino group released by the erythrocyte l...
The Prevalence of Zinc Deficiency in Patients With Thalassemia in South East of Iran,Sistan and Baluchistan Province
Thalassemia Major Zinc Iran
2015/10/14
Background: There are different and controversial reports about zinc deficiency in patients with major thalassemia.
Hydroxyurea Treatment in Transfusion-Dependent β-Thalassemia Patients
Hydroxyurea Blood Transfusion β-Thalassemia
2015/10/13
Background:: β-Thalassemia is an inherited hemoglobin disorder caused by defective synthesis of ß-globin chains. Hemoglobin (Hb) F induction is a possible therapeutic approach which can partially...
Scientists develop simple blood test to track tumour evolution in cancer patients
Scientists develop simple blood test to track tumour evolution in cancer patients
2013/5/27
By tracking changes in patients’ blood, Cambridge scientists have created a new way of looking at how tumours evolve in real-time and develop drug resistance. The research was published in the print e...
Detection of HBV DNA in Cerumen and Sera of Hbsag Negative Patients with Chronic Hepatitis B Infection
HBV DNA Cerumen Sera of Hbsag Negative Patients Chronic Hepatitis B Infection
2015/9/25
Chronic carriers of hepatitis infection are living throughout the world mostly in the South East of Asia.1-5 Recent studies have shown that some HBsAg negative individuals may develop some sort of chr...
Hepatitis C Genotypes in Hemophilia Patients in Iran
Hepatitis C Genotypes Hemophilia Patients
2015/9/22
I genuinely enjoyed reading the excellent and informative original article by Keshvari and colleagues in your journal recently.1 Patients with hemophilia are at greater risk for all forms of viral hep...
Prevalence of the HFE Gene Mutation in the Liver Trans-planted and Primary Hemochromatosis Patients in the Southern Iran
HFE gene Hemochromatosis Liver transplant
2015/9/22
Background: Primary hemochromatosis is an inherited disorder. Mutation in this gene is accompanied with iron overload in the body leading to organ failure that primarily affects liver. Individuals wi...
Prediction of Heart Complications in Thalassemia Major Patients
Prediction Heart Complications Thalassemia Major Patients
2015/9/21
Beta thalassemia major is a chronic hemolytic anemia because of abnormal hemoglobin synthesis. These patients are at risk for iron overload and tissue intoxication. Heart failure is the most common an...
Distribution of Hepatitis C Virus Genotypes in Iranian Patients with Congenital Bleeding Disorders
Hemophilia HCV Genotype Congenital bleeding disorder Iran
2015/9/21
ackground: Chronic hepatitis C virus (HCV) infection is the major cause of liver disease related morbidity and mortality in hemophilic patients who needs regular blood product administration. Although...
Humoral immunity and haemoglobin F (HbF) status in steady state adult Nigerian sickle cell disease patients with asymptomatic malaria
Sickle cell disease malaria parasitaemia immunoglobulins inflammation haemolysis
2010/1/11
Aim: Nigeria, where malaria is prevalent, has the largest sickle cell gene pool in the world. To this end, there is a need for increased understanding of the pathophysiology of HbSS patients in a mala...
SERUM LEVEL MEASUREMENTS OF Gc,Cp,IgG,IgA,AND 1gM IN PATIENTS WITH FAVISM,IN IRAN
G6PD detieieney MEASUREMENTS SERUM
2009/12/30
The quantitative measurements of Gc(P37, C=20); (‘p(P=4O, C=20); lgG(P=67. C= 50);IgA(P- 67,C: :50)and 1gM (P=67,(’=50) were carried out on patients with Favism and healthy individuals, both school bo...
Serum Folate Level Determination in Major Beta Thalassemia Patients
Beta major thalassemia Folic acid Hemoglobin Folate Trace elements
2009/12/14
Objective: Beta major thalassemia is a variant of beta thalassemia syndrome which could be treated with bone marrow transplantation or if not available, regular blood transfusion. In the later group, ...
Rh Subgroups and Kell Antigens in Patients With Thalassemia and in Donors in Turkey
Blood subgroups thalassemia donors
2009/7/2
Alloimmunization can be a significant complication of transfusion therapy in patients with thalassemia and hemoglobinopathies. The aim of this study was to investigate Rh and Kell antigens in patients...
Spontaneous micronuclei in cytokinesis-blocked bone marrow and peripheral blood Iymphocytes of CML patients
Micronucleus assay cytochalasine B bone marrow CML
2009/7/2
Some genetic diseases may have increased cellular instability. Since chronic myloid leukemia (CML) has a genetic base, we aimed to seek the genetic instability of patients by micronucleus analysis, a ...