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TGF-β Signaling May Play a Role in the Development of Goblet Cell Hyperplasia in a Mouse Model of Allergic Rhinitis
allergic rhinitis epithelial cells Smad TGF-β
2010/11/12
In the mouse model of allergic rhinitis, OVA challenge induced phosphorylation of Smad2 predominantly in epithelial cells in the nasal mucosa. In addition, the administration of an inhibitor of TGF-β ...
Antigen-Specific Immunotherapy against Allergic Rhinitis: The State of the Art
allergic rhinitis biomarker immunotherapy pollinosis regulatory T cell
2010/11/12
Allergic rhinitis is the most prevalent type I allergy in industrialized countries. Pollen scattering from trees or grasses often induces seasonal allergic rhinitis, which is known as pollinosis or ha...
The Relationship between Asthma and Allergic Rhinitis in the Iraqi Population
allergen allergic rhinitis allergy asthma
2010/11/16
Background: Recently, extensive research has established that epidemiologic and therapeutic links exist between allergic rhinitis and asthma. The objective of this study was to clarify this associatio...
A Single Center Study of Clinical and Paraclinical Aspects in Iranian Patients with Allergic Rhinitis
Allergic rhinitis Allergens Skin prick test Spirometry
2009/12/15
Allergic rhinitis (AR) is a common form of allergic disorder in Iran and rest of the world. This study was conducted to investigate the symptoms and paraclinical aspects of this allergy among Iranian ...
Prevalence of Allergic Rhinitis in 13-14 Year Old School Children in Hamedan
Allergic Rhinitis ISAAC Allergic shiners Allergen
2009/12/15
Objective: Allergic Rhinitis (AR) is an inflammatory disorder of the nasal mucosa characterized by nasal congestion, rhinorrhea and itching and often accompanied by sneezing and conjuctival irritation...
The Efficacy of Early Treatment of Seasonal Allergic Rhinitis with Benifuuki Green Tea Containing O-methylated Catechin before Pollen Exposure: An Open Randomized Study
'benifuuki' green tea epigallocatechin-3-O- (3-O-methyl)-gallate (EGCG3"Me) Japanese cedar pollinosis long-term pre-seasonal O-methylated catechin
2010/11/16
The nasal symptom medication score in the long-term intake group was significantly lower than that of the short-term intake group at the peak of pollen dispersal. The symptom scores for throat pain, n...
Peroxisome Proliferator-Activated Receptor γ Negatively Regulates Allergic Rhinitis in Mice
allergic rhinitis eosinophils murine model ovalbumin
2010/11/16
Background: Peroxisome proliferator-activated receptor γ(PPAR-γ) has been shown to play an important role in the control of inflammatory responses acting on macrophages, mast cells, T cells, and eosin...
Utility Weights for Allergic Rhinitis Based on a Community Survey with a Time Trade-off Technique in Japan
pollinosis Quality-Adjusted Life Years quality of life seasonal allergic rhinitis utility theory
2010/11/16
Background: Allergic rhinitis is not a fatal disease, but its symptoms deteriorate the quality of life. High morbidity raises a concern about its impact on health care resources. Utility weights, whic...
Clinical Efficacy of Halophilic Lactic Acid Bacterium Tetragenococcus halophilus Th221 from Soy Sauce Moromi for Perennial Allergic Rhinitis
clinical efficacy immunoglobulin E lactic acid bacteria perennial allergic rhinitis soy sauce
2010/11/16
There were no significant differences among the groups that ingested Th221 and the placebo group regarding the disease severities, total nasal symptom scores and total nasal sign scores examined by ph...
Absence of Nasal Blockage in a Japanese Cedar Pollen-Induced Allergic Rhinitis Model Mouse
allergic rhinitis animal model cedar pollen nasal blockage sneezing
2010/11/16
The serum Cry j 1-specific IgE level showed clear elevation only in the group sensitized by Cry j 1 + Al(OH)3 and then challenged by Cry j 1. No elevations were seen in the groups sensitized by pollen...
Analysis of the Comorbidity of Bronchial Asthma and Allergic Rhinitis by Questionnaire in 10,009 Patients
allergen allergic rhinitis asthma exacerbation pollen
2010/11/16
Background: Bronchial asthma (BA) and allergic rhinitis (AR) are thought to share a common pathogenesis. However, reports concerning the comorbidity of the two diseases in a large-scaled population ar...
A new murine model of allergic rhinitis by repeated intranasal Cry j 1 challenge
allergic rhinitis repeated intranasal Cry j 1 challenge
2009/3/2
To evaluate the long-lasting effects of new therapeutic approaches to allergies, we established a new model of allergic rhinitis by repeated challenges with intranasal Cry j 1, a common Japanese ced...
Effect of Local Nasal Immunotherapy on Nasal Blockage in Pollen-Induced Allergic Rhinitis of Guinea Pigs
allergic rhinitis animal model local nasal immunotherapy nasal blockage pollenosis
2010/11/17
Local nasal immunotherapy may be clinically useful for allergic nasal blockage associated with nasal hyperresponsiveness. The mechanisms responsible for this effectiveness might not be related to IgE ...
A Double-Blind Non-inferiority Clinical Study of Montelukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, Compared with Pranlukast in Patients with Seasonal Allergic Rhinitis
comparative double blind study cysteinyl leukotriene receptor montelukast pranlukast seasonal allergic rhinitis
2010/11/17
Montelukast 5mg, 10mg once daily and the pranlukast 450mg/day showed significant improvements in the change from the baseline in the composite, daytime and nighttime nasal symptom scores, and the impr...
Amb a 1-immunostimulatory Oligodeoxynucleotide Conjugate Immunotherapy Increases CD4+CD25+ T Cells in the Nasal Mucosa of Subjects with Allergic Rhinitis
allergic rhinitis Amb a 1-immunostimulatory oligodeoxynucleotide immunotherapy ragweed-pollen allergy regulatory T cell
2010/11/17
The numbers of allergen-induced CD4+-, CD4+CD25+-, IL-10- and TGF-β-positive cells in the nasal mucosa after AIC immunization before the ragweed season did not differ between the two groups. Repeat ch...