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探讨经尿道前列腺电切术同期行腹股沟疝修补术在良性前列腺增生症(BPH)合并腹股沟疝患者中的临床应用效果。方法 将2016年7月至2019年7月台山市第二人民医院收治的60例BPH合并腹股沟疝患者以随机数表法分为观察组和对照组,每组 30例,观察组同期施行经尿道前列腺增生等离子电切术(PKURP)与腹腔镜下全腹膜外腹股沟疝修补术(TEP),对照组则分期实施PKURP术与TEP术,比较两组患者的术中出...
探究白藜芦醇(Resveratrol)在前列腺增生上皮细胞系BPH-1中的作用及可能的机制。方法用不同浓度的白藜芦醇处理BPH-1细胞,处理24 h后用MTT法、流式细胞术等方法测不同白藜芦醇对BPH-1的作用,Western blot测定不同浓度白藜芦醇作用后相关蛋白的表达及改变,探究其作用可能的机制。结果白藜芦醇处理BPH-1细胞24 h及48 h后,细胞生长明显受抑制,且呈浓度、时间依赖性;...
良性前列腺增生患者生命质量量表QLICD-BPH研制与评价
良性前列腺增生(BPH) 生命质量 量表 考评
2014/5/26
研制良性前列腺增生患者生命质量测定量表(QLICD-BPH)并对其进行评价。方法 依据慢性病患者生命质量测定量表体系共性模块与特异模块相结合的研究思想,在对文献回顾的基础上,结合中国文化特色,采用量表开发的程序化决策方式研制量表,并通过测试141例良性前列腺增生(BPH)患者的生命质量对量表进行评价。结果 QLICD-BPH量表的重测信度为0.95;Cronbach’s α系数为0.91;分半信度...
BPH-1通过分泌前列腺素E2促进前列腺间质细胞芳香化酶的表达
BPH-1 芳香酶 前列腺素E2
2009/6/9
目的:研究前列腺上皮细胞旁分泌对间质细胞芳香化酶表达的影响。方法:用前列腺上皮细胞系(BPH-1, LNCap, DU145, PC3)条件培养液(CM)处理间质细胞,用RT-qPCR和Western blotting检测芳香化酶表达水平。用RT-qPCR和ELISA检测上皮细胞系环氧合酶2(COX-2)的表达及其CM前列腺素E2(PGE2)浓度。用添加COX-2特异性抑制剂NS-398的培养液培...
Androgen concentrations and their receptors in the periurethral region are higher than those of the subcapsular zone in benign prostatic hyperplasia(BPH)
Testosterone DHT 3cs-androstanediol
2009/2/17
Benign prostatic hyperplasia (BPH) is an androgen-dependent disease that initially develops in the inner prostate, where the highest concentrations of testosterone (T) and dihydrotestosterone (DHT) ...
Androgen concentrations and their receptors in the periurethral region are higher than those of the subcapsular zone in benign prostatic hyperplasia(BPH
Testosterone DHT 3cs-androstanediol
2009/2/17
Benign prostatic hyperplasia (BPH) is an androgen-dependent disease that initially develops in the inner prostate, where the highest concentrations of testosterone (T) and dihydrotestosterone (DHT) ...
Prevalent decrease of the EGF content in the periurethral zone of BPH tissue induced by treatment with finasteride or flutamide
EGF content periurethral zone BPH flutamide
2009/2/17
The aim of the present investigation is to verify whether treatment with Finasteride or Flutamide influences the regional distribution of testosterone (T), dihydrotestosterone (DHT), and epidermal g...