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Molecular and genetic characterization of the 10.4 kDa cytoplasmic dynein light chain and its effects on the neuroanatomy of {\it Drosophila\/}
Molecular and genetic tools neural development gene causes axis the cytoplasm protein light chain gene
2014/12/11
We utilized the powerful molecular and genetic tools available for the analysis of neural development in Drosophila to characterize a mutation for its effects on imaginal sensory axons. Previous analy...
Characterization of arachidonic acid -mediated signal transduction in regulation of NIH -3T3 cell adhesion to extracellular matrix
Matrix the discrete form cells cell proliferation lipid protein cell fibronectin
2014/12/11
Cell-extracellular matrix (ECM) adhesion is characterized by discrete morphological and functional stages beginning with cell-substrate attachment, followed by cell spreading and then migration. These...
Formation and plasticity of glutamatergic synapses: Characterization of the roles of beta-amyloid precursor protein, scribble, and wingless at the Drosophila neuromuscular junction
Neurons circuit static core
2014/12/11
The flow of information through neuronal circuits relies on the ability of neurons to form synaptic connections with specific temporal and spatial properties. These properties are not static but have ...
Cloning and functional characterization of the zebrafish mutation belladonna
Belladonna zebrafish mutations mutagenic screen and identify genes the retina the nerve cross the pupil
2014/12/11
The zebrafish belladonna (bel) mutation was identified in a large-scale mutagenesis screen to identify genes involved in retino-tectal pathfinding in Tubingen, Germany. In bel mutants, after exiting t...
Characterization of bendless and interacting partners in Drosophila central synapse formation
Neurons signaling pathways websites molecular nervous system diseases diseases central synapses fiber system the neural network
2014/12/11
Synapses are the functional units of neuronal circuits and the sites of integration for multiple signaling pathways. Understanding the molecular basis of synaptic function is critical to understanding...
Identification and Functional Characterization of the Zebrafish Gene Quetschkommode (que)
dbt disease models metabolism MSUD neurodegenerative diseases zebrafish
2014/12/10
Locomotion in vertebrates depends on proper formation and maintenance of neuronal networks in the hind-brain and spinal cord. Malformation or loss of factors required for proper maintenance of these n...
THE IDENTIFICATION AND CHARACTERIZATION OF A GROUP OF ER TPR-CONTAINING ADAPTER PROTEINS
cell biology endoplasmic reticulum tetratricopeptide repeats endoplasmic reticulum compartmentalization calcium homeostasis adapter proteins
2014/12/10
The endoplasmic reticulum (ER) is an organelle responsible for a variety of functions in all eukaryotic cells. Some of these functions are localized to specific regions in the ER, such as the ribosome...
Characterization of Hepatitis C Virus Infection of Hepatocytes and Astrocytes
exosome IL-18, 3D live cell imaging
2015/5/21
Approximately 2.8% of the world population is currently infected with hepatitis C virus (HCV). Neutralizing antibodies (nAbs) are often generated in chronic hepatitis C patients yet fail to control th...