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Improving the sensitivity of protein-protein interaction detection and protein structure probing is a principal challenge in cross-linking mass spectrometry (XL-MS) data analysis. In this talk, we pro...
After decades of fundamental scientific and drug discovery research, Alzheimer’s disease has remained inscrutable and incurable, with a bare minimum of therapeutic progress. But in a new review articl...
自从科学家们研究清楚CRISPR-Cas系统的作用机理并将其应用于真核细胞的基因编辑后,相关工具的开发、改造和应用呈爆发式增长,成为生物学研究的重要手段。目前主要的CRISPR编辑工具有Cas9、Base editor (BE)和Prime editor (PE),及衍生的各种工具。CRISPR编辑工具在基因功能研究、转录调控、表观遗传修饰和基因治疗等众多研究领域具有重要应用和广阔前景。但是,CR...
Background: The ω-6 (n–6) to ω-3 (n–3) fatty acid (FA) ratio (n–6:n–3 ratio) was previously shown to be a predictor of executive function performance in children aged 7–9 y.
Background: Aging is associated with a progressive decline in vitamin B-12 status. Overt vitamin B-12 deficiency causes neurologic disturbances in peripheral and central motor and sensory systems, but...
This study assessed the influence of genetic type (Embden-Anser anser, EE; Toulouse-Anser anser, TT and F1 cross, ET) for meat characteristics (carcass, meat quality and fatty acid (FA) profiles), of ...
A study was conducted to assess the genetic diversity among Simmental Cross cattle in West Sumatra using microsatellite DNA markers. A total of 176 individual cattle blood samples was used for obtaini...
Raymond K. Cross, Jr., M.D.,M.S. is a board certified Gastroenterologist and Associate Professor of Medicine, Division of Gastroenterology and Hepatology, at the University of Maryland School of Medic...
Background: Age-related progressive loss of muscle mass is an increasing problem in our aging society, affecting physical ability, risk of falls, and need for health care. Telomere length has been rec...
Carbohydrates (CHOs), branched-chain amino acids (BCAAs) and caffeine are known to improve running performance. However, no information is available on the effects of a combination of these ingredien...
The heart is the first organ to form during development in vertebrates and Nkx2-5 is the first marker of cardiac specification. In Xenopus laevis, Nkx2-5 is essential for heart formation, but early ta...
The purpose of this study was to detect significant SNPs for blood components that were related to immunity using high single nucleotide polymorphism (SNP) density panels in a Korean native pig (KNP)×...
A whole genome association (WGA) study was performed to detect significant polymorphisms for meat quality traits in an F2 cross population (N = 478) that were generated with Korean native pig sires an...
In Erhualian and Yorkshire reciprocal cross F1 pig populations, we examined the mRNA expression characteristic of liver-derived IGF-1, IGF-1R, IGF-2, IGF-2R and IGFBP-3 during the embryonic and postna...
Marker-assisted gene pyramiding aims to produce individuals with superior economic traits according to the optimal breeding scheme which involves selecting a series of favorite target alleles after cr...

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