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中国免疫学会胡卓伟团队《Immunity》发文揭示泛素编辑酶A20调控肺纤维化发病的重要机制（图）
中国免疫学会 胡卓伟 团队 Immunity 泛素 编辑酶 A20 肺纤维化 重要机制
2019/9/25
2019年8月27日，中国医学科学院药物研究所天然药物活性物质与功能国家重点实验室胡卓伟研究员团队在肺纤维化发病的分子机制研究方面取得重要进展，该研究以“Targeting the Transcriptional Factor C/EBPβ Degradation Reduces Lung Fibrosis by Restoring Activity of the Ubiquitin-Editin...
Sensitivity analysis of a computational model of the IKK-NF-κB-IκBα-A20 signal transduction network
Sensitivity analysis computational model IKK-NF-κB-IκBα-A20 signal transduction
2010/11/15
The NF-{\kappa}B signaling network plays an important role in many different compartments of the immune system during immune activation. Using a computational model of the NF-{\kappa}B signaling netw...
Noise-induced oscillatory shuttling of NF-κB in a two compartment IKK-NF-κB-IκB-A20 signaling model
Noise-induced oscillatory shuttling NF-κB two compartment IKK-NF-κB-IκB-A20 signaling model
2010/11/15
NF-{\kappa}B is a pleiotropic protein whose nucleo-cytoplasmic trafficking is tightly regulated by multiple negative feedback loops embedded in the NF-{\kappa}B signaling network and contributes to di...