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Impact Of Hepatitis C Co-Infection On CD4 Cell Count In HIV Infected Subjects
Hepatitis C Human Immunodeficiency virus CD4 cell count Co-infection
2015/7/28
Background: Human immunodeficiency virus (HIV) and Hepatitis C virus (HCV) co-infection is reported to be common among HIV infected subjects due to share routes of transmission. The fact that HCV infe...
Red Cell Genetic Markers in Malarial Susceptibility and Selective Advantage Hypothesis
Red cell genetic markers Hemoglobin E G6PD deficiency Malaria susceptibility Natural selection North-Eastern India
2015/6/10
Malaria is still a serious public health challenge in many parts of the world including India. Human genetic susceptibility to malaria varies from individual to individual depending upon the genetic c...
CIS REGULATORY MODULE DISCOVERY IN TH1 CELL DEVELOPMENT
TH1 cell development STAT4 ChIP-on-chip ChIP-Seq
2015/5/26
Immune response enables the body to resist foreign invasions. The Inflammatory response is an important aspect in the immune response which is articulated by elements such as cytokines, APC, T-cell an...
The Regulatory Role Of Matrix Metalloproteinases In T Cell Activation
T cell activation MMP9 Matrix Metalloproteinases
2015/5/25
Introduction: Matrix metalloproteinases (MMPs) are known for their role in extracellular matrix remodeling, but their role in regulating intracellular immune cell function is unknown. We reported that...
DIFFERENTIAL ROLE OF PI-3KINASE p85 (α & β) REGULATORY SUBUNITS IN MAST CELL DEVELOPMENT
Cell cycle -- Regulation Enzymes
2015/5/25
Stem cell factor (SCF) mediated c-Kit signaling, and downstream activation of Phosphatidylinositol-3 Kinase (PI-3K) is critical for multiple biological effects mediated by mast cells. Mast cells expre...
ERK1 AND ERK2 IN HEMATOPOIESIS, MAST CELL FUNCTION, AND THE MANAGEMENT OF NF1-ASSOCIATED LEUKEMIA AND TUMORS
hematopoiesis neurofibroma leukemia
2015/5/25
Neurofibromatosis type 1 is a genetic disease that results from either heritable or spontaneous autosomal dominant mutations in the NF1 gene, which encodes a protein serving, at least in part, to acce...
THE ROLE OF CERAMIDES IN CIGARETTE SMOKE-INDUCED ALVEOLAR CELL DEATH
The complex pathogenesis emphysema involves disappearance
2015/5/25
The complex pathogenesis of emphysema involves disappearance of alveolar structures, in part attributed to alveolar cell apoptosis. The mechanism by which cigarette smoke (CS) induces alveolar cell ap...
Mechanisms of translational regulation in the pancreatic β cell stress response
Diabetes Islet ER stress Pdx1
2015/5/22
The islet beta cell is unique in its ability to synthesize and secrete insulin for use in the body. A number of factors including proinflammatory cytokines, free fatty acids, and islet amyloid are kno...
Bone cell-independent benefits of raloxifene on the skeleton: A novel mechanism for improving bone material properties
mechanical testing raloxifene toughness water bone loss
2014/12/4
Raloxifene is an FDA approved agent used to treat bone loss and decrease fracture risk. In clinical trials and animal studies, raloxifene reduces fracture risk and improves bone mechanical properties,...
A phenomenological model for the dynamics of cell cycle in responding to X-rays
DNA repair G2 arrest G1 arrest Computational model Ionizing radiation
2015/9/6
To establish a model to predict the cell-cycle process in response to ionizing radiation.Methods Human choroidal malignant melanoma 92-1 cells were used and the cell cycle distribution of cells was an...
The Effects of Insulin-Like Growth Factor-1 Gene Therapy and Cell Transplantation on Rat Acute Wound Model
IGF-1 Gene Therapy Cell Transplantation Fibroblast Wound Healing
2015/10/15
Background: Wound healing is a complex process. Different types of skin cells, extracellular matrix and variety of growth factors are involved in wound healing. The use of recombinant growth factors i...
Construction of Recombinant Bacmid Containing M2e-Ctxb and Producing the Fusion Protein in Insect Cell Lines
Influenza Vaccines Baculovirus Cholera Toxin Subunit B
2015/10/10
Background:: Sequence variations in glycoproteins of influenza virus surface impel us to design new candidate vaccines yearly. Ectodomain of influenza M2 protein is a surface and highly conserved prot...
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厦门大学医学院卜国军教授课题组在Cell子刊发表研究论文(图)
卜国军 论文 医学
2014/9/30
厦门大学神经科学研究所暨福建省神经退行性疾病及衰老研究重点实验室的国家“千人计划”特聘教授卜国军所领导的课题组,针对LRP6介导的Wnt信号在神经突触和认知功能方面的作用开展了深入研究,最近取得了突破性的成果,发表在最新出版的神经科学领域最权威的刊物《Cell》子刊《Neuron》(JCR一区,影响因子15.98),题目为”Deficiency in LRP6-Mediated Wnt Signa...
复旦大学上海医学院人体生理学课件Chapter 2 BASIC FUNCTIONS OF THE CELL
复旦大学上海医学院 人体生理学 课件 Chapter 2 BASIC FUNCTIONS OF THE CELL
2014/9/22
复旦大学上海医学院人体生理学课件Chapter 2 BASIC FUNCTIONS OF THE CELL。
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2014年5月5日,生化与细胞所陈玲玲课题组在《细胞研究》(Cell Research)发表当期封面文章“Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus”。该工作获得长非编码RNA研究领域著名科学家美国哈佛大学John L. Ri...