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Background: Human immunodeficiency virus (HIV) and Hepatitis C virus (HCV) co-infection is reported to be common among HIV infected subjects due to share routes of transmission. The fact that HCV infe...
Malaria is still a serious public health challenge in many parts of the world including India. Human genetic susceptibility to malaria varies from individual to individual depending upon the genetic c...
Immune response enables the body to resist foreign invasions. The Inflammatory response is an important aspect in the immune response which is articulated by elements such as cytokines, APC, T-cell an...
Introduction: Matrix metalloproteinases (MMPs) are known for their role in extracellular matrix remodeling, but their role in regulating intracellular immune cell function is unknown. We reported that...
Stem cell factor (SCF) mediated c-Kit signaling, and downstream activation of Phosphatidylinositol-3 Kinase (PI-3K) is critical for multiple biological effects mediated by mast cells. Mast cells expre...
Neurofibromatosis type 1 is a genetic disease that results from either heritable or spontaneous autosomal dominant mutations in the NF1 gene, which encodes a protein serving, at least in part, to acce...
The complex pathogenesis of emphysema involves disappearance of alveolar structures, in part attributed to alveolar cell apoptosis. The mechanism by which cigarette smoke (CS) induces alveolar cell ap...
The islet beta cell is unique in its ability to synthesize and secrete insulin for use in the body. A number of factors including proinflammatory cytokines, free fatty acids, and islet amyloid are kno...
Raloxifene is an FDA approved agent used to treat bone loss and decrease fracture risk. In clinical trials and animal studies, raloxifene reduces fracture risk and improves bone mechanical properties,...
To establish a model to predict the cell-cycle process in response to ionizing radiation.Methods Human choroidal malignant melanoma 92-1 cells were used and the cell cycle distribution of cells was an...
Background: Wound healing is a complex process. Different types of skin cells, extracellular matrix and variety of growth factors are involved in wound healing. The use of recombinant growth factors i...
Background:: Sequence variations in glycoproteins of influenza virus surface impel us to design new candidate vaccines yearly. Ectodomain of influenza M2 protein is a surface and highly conserved prot...
厦门大学神经科学研究所暨福建省神经退行性疾病及衰老研究重点实验室的国家“千人计划”特聘教授卜国军所领导的课题组,针对LRP6介导的Wnt信号在神经突触和认知功能方面的作用开展了深入研究,最近取得了突破性的成果,发表在最新出版的神经科学领域最权威的刊物《Cell》子刊《Neuron》(JCR一区,影响因子15.98),题目为”Deficiency in LRP6-Mediated Wnt Signa...
2014年5月5日,生化与细胞所陈玲玲课题组在《细胞研究》(Cell Research)发表当期封面文章“Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus”。该工作获得长非编码RNA研究领域著名科学家美国哈佛大学John L. Ri...

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