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目前,食管癌的发病率与死亡率在全球范围内均排在前列,超过一半以上的患者发生在我国,其中约90%的病理类型为食管鳞状细胞癌(esophageal squamous cell carcinoma,ESCC)。通过以往的研究发现,食管鳞癌在基因组变异和肿瘤微环境等方面均具有广泛的肿瘤异质性,而造成食管鳞癌异质性的原因尚不清楚。因此,充分了解肿瘤异质性的特征以及其形成机制将有助于指导食管鳞癌药物开发以及临...
Boreal forests constitute a large portion of the global forest area, yet they are undersampled through field surveys, and only a few remotely sensed data sources provide structural information wall-to...
Many studies have shown that the weather greatly affects the tourist count. Understanding weather information, climate change, and how they influence the tourist count in different tourist seasons (pe...
Forest inventory data (FID) are important resources for understanding the dynamics of forest carbon cycling at regional and global scales. Developing carbon storage growth models and analyzing the dif...
Habitat spatial distribution is essential to know where to focus the protection of the seafloor resources. In this work, the bathymetry and backscatter seabed data show the importance of remote sensin...
The Chinese government has already proposed to build a nature protected area system composed mainly of national parks and encourages the development of concession operations in national parks. The est...
El Teide National Park on the island of Tenerife (Canary Islands) is home to one of the most spectacular volcanic landscapes in the world. Although the conservation of its geodiversity is not a major ...
The development of China's national parks is still in the initial stage, and few scholars have studied the effects of soundscapes on human physiology and psychology from the perspective of the auditor...
Monitoring visitor demographics and temporal visitation patterns can help national park managers understand their visitors and allocate resources more effectively. Traditional approaches, such as visi...
Due to rising global warming and climate change, biodiversity protection has become a critical ecological concern. Rich biodiversity zones are under threat and are deteriorating, necessitating nationa...
A soil scientist, a virologist, a molecular biologist and a biophysicist are Cornell’s 2023 electees to the National Academy of Sciences (NAS), the academy announced May 2 at the close of its 160th an...
Karen Vogtmann, Goldman Smith Professor of Mathematics Emeritus in the College of Arts and Sciences, has been elected to the National Academy of Sciences (NAS).
2022年6月24日,山西农业大学与中国科学院微生物研究所联合署名,在《National Science Review》(最新影响因子23.178)上在线发表题为“Cross-species recognition and molecular basis of SARS-CoV-2 and SARS-CoV binding to ACE2s of marine animals”的研究性论文。
N-糖基化是蛋白质最普遍、复杂及重要的一种翻译后修饰之,位点特异的完整糖肽分析不仅能反映出特定糖型变化,并且可以指向特定的肽段及蛋白,近年来日益受到关注。然而,由于糖苷键和肽键碎裂能量不一致,各种质谱碎裂方式都只能获得部分定性信息,如高能碰撞裂解模式(Higher energy dissociation,HCD)下糖链产生糖和b/y型肽段片段,但可能导致在碎裂过程中失去全部或部分糖链修饰,而电子转...
National Science Review在线发表了中国科学院分子细胞科学卓越创新中心研究员季红斌研究组和中科院数学与系统科学研究院研究员王勇研究组合作的题为Identification of TAZ as the essential molecular switch in orchestrating SCLC phenotypic transition and metastasis的研究论文...

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