搜索结果: 1-15 共查到“DNA methylation”相关记录15条 . 查询时间(0.114 秒)
南京农业大学农学院《Nucleic Acids Research》发表张文利教授团队“The roles of DNA methylation on pH dependent i-motifs (iMs) formation in rice”（图）
张文利 基因 解析
2024/6/11
2024年1月8日，农学院张文利课题组在 “Nucleic Acids Research”上发表了题为“The roles of DNA methylation on pH dependent i-motifs (iMs) formation in rice”的研究论文。该研究是在前期的研究基础之上（Nucleic Acids Res 2022, 50:3226-3238），再次利用iM-IP-s...
UVR8 interacts with de novo DNA methyltransferase and suppresses DNA methylation in Arabidopsis
DNA methylation Light responses Plant signalling
2023/12/11
DNA methylation is an important epigenetic gene regulatory mechanism conserved in eukaryotes. Emerging evidence shows DNA methylation alterations in response to environmental cues. However, the mechan...
南京农业大学农学院《Plant Cell》发表宋庆鑫教授团队“Asymmetric variation of DNA methylation during domestication and de-domestication of rice”（图）
宋庆鑫 水稻栽培 基因
2023/10/28
水稻是全球最为重要的粮食作物之一，在其漫长的驯化过程中形成了形态各异的水稻栽培亚型，包括粳稻、籼稻、Aro和Aus等。在水稻栽培种植历史过程中，有些水稻逐渐恢复部分野生稻表型特征，最终演化成严重威胁全球水稻产量的杂草稻，这种现象称之为“去驯化”。通过基因组进化研究发现，大量驯化位点的变异在去驯化过程中并不能得到恢复，这就暗示着可能存在别的遗传机制来调控杂草稻在去驯化过程中恢复野生稻表型。DNA甲基...
南京农业大学农学院《PNAS》发表水稻抗病遗传育种课题组“The effect of RNA polymerase V on 24-nt siRNA accumulation depends on DNA methylation contexts and histone modifications in rice”（图）
水稻抗病 遗传育种 转基因育种
2022/3/23
2021年7月22日，“作物遗传与种质创新国家重点实验室”的水稻抗病遗传育种课题组在《PNAS》在线发表了题为“The effect of RNA polymerase V on 24-nt siRNA accumulation depends on DNA methylation contexts and histone modifications in rice”的研究论文（Article）。...
DHA-rich n–3 fatty acid supplementation decreases DNA methylation in blood leukocytes: the OmegAD study
fish oil DHA EPA DNA methylation LINE-1 Alzheimer disease
2018/11/20
Background: Dietary fish oils, rich in long-chain n–3 (ω-3) fatty acids (FAs) [e.g., docosahexaenoic acid (DHA, 22:6n–3) and eicosapentaenoic acid (EPA, 20:5n–3)], modulate inflammatory reactions thro...
Impact of polyunsaturated and saturated fat overfeeding on the DNA-methylation pattern in human adipose tissue: a randomized controlled trial
DNA methylation epigenetics EWAS Illumina 450k methylation array LIPOGAIN cohort obesity overfeeding polyunsaturated fat prediction saturated fat
2018/11/13
Background: Dietary fat composition can affect ectopic lipid accumulation and, thereby, insulin resistance. Diets that are high in saturated fatty acids (SFAs) or polyunsaturated fatty acids (PUFAs) h...
Repeats as global DNA methylation marker in bovine preimplantation embryos
epigenetics retrotransposon bisulfite sequencing
2017/2/21
DNA methylation undergoes dynamic changes and is a crucial part of the epigenetic regulation during mammalian early development. To determine the DNA methylation levels in bovine embryos, we applied a...
Postprandial alterations in whole-blood DNA methylation are mediated by changes in white blood cell composition
DNA methylation food intake ghrelin HumanMethylation450k EWAS
2018/12/13
Background: DNA methylation is an essential nuclear process associated with genomic functions such as transcription factor binding and the regulation of gene expression. DNA methylation patterns can a...
LIM homeodomain 3 (LHX3) is an important regulator of pituitary and nervous system development. To date, twelve LHX3 gene mutations have been identified in patients with combined pituitary hormone def...
Association of DNA Methylation Levels with Tissue-specific Expression of Adipogenic and Lipogenic Genes in Longissimus dorsi Muscle of Korean Cattle
Adipogenesis DNA Methylation Intramuscular Fat Korean Cattle
2016/5/17
Epigenetic factors, such as DNA methylation status, may regulate adipogenesis and lipogenesis, thus affecting intramuscular fat (IMF) deposition in longissimus dorsi muscle (LM) of beef cattle. In Kor...
Does DNA Methylation Plays a Critical Role in Osteoblastic Differentiation of Mesenchymal Stem Cells (MSCs)?
Mesenchymal Stromal Cells Cell Differentiation Osteoblastic
2015/10/8
Mesenchymal stem cells (MSCs) are characterized by ability to differentiate into several cell types and self-renewability. These stem cells have a limited capacity in cell lineage differentiation incl...
DNA甲基化与组蛋白甲基化的关系The Relationship of DNA Methylation and Histone Methylation
DNA 组蛋白 甲基化 甲基转移酶
2008/1/10
摘要在真核生物基因组及基因组以外，存在着多种共价修饰，其中，DNA和组蛋白的甲基化都与基因的沉默存在着联系，DNA和H3K9的甲基化在调节基因过程中具有协同作用，并拮抗H3K4的甲基化。近来的研究显示，两种甲基化机制之间似乎还存在着联系，即DNA的甲基化可能依赖于H3K9的甲基化，但在哺乳动物中，两种甲基化的关系可能更复杂。 Abstract: In and out of the eukaryot...
Genome-wide DNA Methylation Profiles of Small Intestine and Liver in Fast-growing and Slow-growing Weaning Piglets
DNA Methylation MBD-seq Epigenetic Profile Weaning Piglet Genome-wide Methylation Profile
2016/5/17
Although growth rate is one of the main economic traits of concern in pig production, there is limited knowledge on its epigenetic regulation, such as DNA methylation. In this study, we conducted meth...
Genomic DNA methylation decreases in response to moderate folate depletion in elderly women
DNA methylation genomic DNA folate homocysteine humans elderly women
2016/6/8
Background: Methylation of genomic DNA is dependent on an
adequate supply of folate coenzymes. Previous data support the
hypothesis that abnormal DNA methylation plays an integral
role in carcinoge...
Folate, DNA methylation, and gene expression: factors of nature and nurture
nature and nurture nature and nurture
2016/6/8
Folate provides the one-carbon units required for purine and
thymidylate syntheses and for methylation of a wide variety of
essential biological substances, including phospholipids, proteins,
DNA, ...