搜索结果: 1-2 共查到“生物医学工程 Foxp3”相关记录2条 . 查询时间(0.077 秒)
近期，中科院上海巴斯德研究所李斌课题组与约翰·霍普金斯大学医学院潘凡实验室开展的合作研究取得阶段性进展：通过生化及分子免疫学研究手段与疾病动物模型等实验方法紧密结合，他们发现了一个有趣的LPS-TLR4-Myd88-Stub1-FOXP3 负调节通路, 揭示了炎症情况下导致FOXP3+调节性T细胞免疫抑制功能失活的分子新机制，对进一步深入理解炎症环境下FOXP3+调节性T细胞功能稳定性及其调节具有...
Neutralization of IL-4 and IFN-γ Facilitates inducing TGF-β-induced CD4+Foxp3+ Regulatory Cells
suppressor/regulatory T cells cytokine Foxp3 autoimmunity
2009/4/29
It has been well recognized that TGF-β is able to induce CD4+CD25+Foxp3+ suppressor/regulatory T (iTreg) cells and IL-2 facilitates iTreg induction and expansion, however, only half of TGF-β-induced C...