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An inhibitor of the mitotic kinase, MPS1, is selective towards pancreatic cancer cells
CIN70 MPS1 kinase inhibitor pancreatic cancer
2015/5/21
The abysmal five year pancreatic cancer survival rate of less than 6% highlights the need for new treatments for this deadly malignancy. Cytotoxic drugs normally target rapidly dividing cancer cells b...
Combination therapy with cell-binding domain,angiogenesis inhibitor and Ca2+ channel blocker in mice metastatic model
Metastasis Cell-binding domain Fibronectin Angiogenesis inhibitor Ca2+ channel blocker
2009/7/15
Background: In order to prevent tumor metastasis, we investigated more effective inhibition by combination therapy. The competition with native adhesion molecules by cell-binding domain, inhibition of...