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The effects of aging on the seminiferous epithelium and the blood-testis barrier of the Brown Norway rat
seminiferous epithelium blood-testis barrier Brown Norway rat
2009/2/18
Steroidogenesis and spermatogenesis decrease in aging Brown Norway rats. We therefore hypothesized that there must be accompanying morphological changes taking place in the seminiferous tubules of...
Long-term alterations in the permeability of the blood-testis barrier following a single intratesticular injection of dilute aqueous glycerol
Blood-testis barrier permeability glycerol seminiferous tubules Sertoli cells
2009/2/12
The mechanism whereby glycerol exerts its antispermatogenic action is not known. The objective of this study was to determine, with the use of [3H]inulin and [125I]albumin by in vivo and in vitro ...
Pituitary adenylate cyclase activating polypeptide（PACAP）can cross the vascular component of the blood-testis barrier in the mouse
Influx constants transport peptide T vasoactive intestinal polypeptide
2009/2/12
Pituitary adenylate cyclase activating polypeptide (PACAP), present in highest concentrations in the hypothalamus and testes, affects the release of LH, FSH, and prolactin, as well as Sertoli cell...
Human interleukin-1 alpha crosses the blood-testis barriers of the mouse
Cytokine Sertoli cell transport blood-brain barrier germinal cells
2009/2/10
Interleukin-1 alpha (IL-1 alpha) has been shown to have direct effects on the gonads, affecting steroidal secretion, DNA synthesis by spermatogonia, and the immune function of the testes. It is un...
Neonatally administered diethylstilbestrol retards the development of the blood-testis barrier in the rat
diethylstilbestrol blood-testis rat
2008/12/26
Newborn rats were treated with 10 microg of diethylstilbestrol (DES) on alternate days from the 2nd to the 12th postnatal day, and the testes were sequentially examined up to 105 days of age by light,...
The effect of cardiac arrest on the blood-testis barrier to albumin, tumor necrosis factor-alpha, pituitary adenylate cyclase activating polypeptide, sucrose, and verapamil in the mouse
blood-testis albumin tumor necrosis factor-alpha pituitary adenylate cyclase
2008/12/26
Impotence commonly occurs after events such as acute myocardial infarction, coronary bypass, head trauma, and cerebral bleeding, including subarachnoid hemorrhage. We hypothesize that the hypoxia ac...