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Identification of a potential FSH modulatory protein in human testis and seminal plasma
potential FSH modulatory protein human testis seminal plasma
2009/2/23
A variety of factors capable of inhibiting the in vitro binding of FSH to its receptor have been identified in gonadal tissues from males and females. Interest in these factors has been stimulated b...
Transferrin secretion in response to different modes of FSH stimulation and cycloheximide in superfused Sertoli cell cultures
Transferrin secretion FSH stimulation cycloheximide superfused Sertoli cell cultures
2009/2/23
The influence of different modes of FSH stimulation and cycloheximide on transferrin secretion by rat Sertoli cells was investigated using a superfusion culture system. Sertoli cells from 18-day-old...
Increased plasma and pituitary prolactin concentrations in adult male rats with selective elevation of FSH levels may be explained by reduced testosterone and increased estradiol production
Increased plasma pituitary prolactin concentrations adult male rats
2009/2/23
The roles of testosterone and estradiol in regulating prolactin concentrations were studied in acutely castrated adult male rats receiving subcutaneous Silastic implants of the sex steroids. Testost...
Low molecular weight FSH binding inhibitor in bovine testis
Low molecular weight FSH bovine testis
2009/2/23
Purification of low Mr (less than 5000) inhibitors of FSH binding to receptors has been hampered by their low concentration in tissue extracts and physiologic fluids. The calf testis represents an a...
Changes in serum levels of LH, FSH, prolactin, testosterone, and cortisol associated with season and mating in male pygmy goats
serum levels LH FSH prolactin testosterone cortisol season male pygmy goats
2009/2/20
Four male pygmy goats were used in a study designed to determine the effects of season on serum hormone (luteinizing hormone, follicle stimulating hormone, prolactin, testosterone, and cortisol) l...
Role of the pineal in the alteration of hamster Sertoli cell responsiveness to FSH during testicular regression
pineal hamster Sertoli cells testicular regression short photoperiod optic enucleation
2009/2/20
Testicular regression was induced in adult hamsters by optic enucleation, short photoperiod, or melatonin injections. The melatonin injected group, while undergoing testicular regression, showed a q...
Clinical studies in an adult male patient with “isolated follicle stimulating hormone (FSH)deficiency”
isolated FSH deficiency gonadotropin deficiency hypogonadism infertility FSH deficiency
2009/2/20
Previous reports concerning isolated follicle stimulating hormone (FSH) deficiency and its possible pathogenesis have been conflicting. Both "normal" and "abnormal" FSH response to luteinizing hormone...
Individual differences in LH and FSH responses to orchidectomy and testosterone replacement therapy in rams
Individual differences LH FSH rams
2009/2/19
Profiles of LH and FSH levels and pituitary LH responses to exogenous luteinizing hormone releasing hormone (LHRH) have been characterized in rams, castrated rams (wethers), and wethers implanted wi...
Modification of Sertoli Cell Responsiveness to FSH by Cryptorchidism and Hypophysectomy in Immature and Adult Rats
rat cryptorchidy hypophysectomy cAMP Sertoli cell
2009/2/19
Cryptorchid or hypophysectomized rats were used as models to examine the possible relationships between germ cell development and gonadotropins in the agerelated decline in the responsiveness of t...
FSH Stimulation of cAMP Accumulation in Hamster Sertoli Cells:Effect of Age and Optic Enucleation
cAMP Sertoli cells hamsters optic enucleation
2009/2/19
Sertoli cells isolated from immature, adult, and adult optic-enucleated hamsters respond to FSH, but not to LH, with an increase in cAMP accumulation. There is an age-related decline in responsivene...
A Possible Relation between Elevated FSH Levels and Leydig Cell Dysfunction in Azoospermic and Oligospermic Men
follicle-stimulating hormone luteinizing hormone testosterone oligospermia
2009/2/18
Plasma testosterone, follicle-stimulating hormone (FSH), and luteinizing hormone (LH) levels were measured in the male partners of 69 infertile couples and in 260 allegedly fertile men requesting va...
FSH immunoneutralization acutely impairs spermatogonial development in normal adult rats
FSH immunoneutralization spermatogonial development adult rats
2009/2/18
Follicle-stimulating hormone (FSH) plays an important part in testicular development. Its role in the regulation of spermatogenesis in the adult, however, remains controversial. This study aimed t...
Sodium chlorate induces undersulfation of cellular proteoglycans and increases in FSH-stimulated estradiol production in immature rat Sertoli cells
Sodium chlorate cellular proteoglycans FSH-stimulated estradiol production immature rat Sertoli cells
2009/2/18
The functional influence of cell proteoglycan (PG) undersulfation on estradiol synthesis by immature rat Sertoli cell cultures was investigated by using sodium chlorate, an inhibitor of the active s...
We have previously demonstrated that conditioned medium from testicular macrophages stimulates testosterone production by Leydig cells. It was also reported that conditioned medium from macrophage...
Hormonal regulation of spermatogenesis in the hypophysectomized rat:FSH maintenance of cellular viability during pubertal spermatogenesis
Testis testosterone hypohysectomy cellviability
2009/2/17
The potential for follicle-stimulating hormone (FSH) to promote germ-cell survival and the cellular sites of FSH action were studied using a gonadally maturing (pubertal), hypophysectomized (Hx) rat...