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Quantitative（stereological）study of the normal spermatogenesis in the adult monkey（Macaca fascicularis）
normal spermatogenesis adult monkey
2009/2/17
Germ cell and Sertoli cell numbers were estimated in six normal adult monkeys (Macaca fascicularis) using a contemporary unbiased and efficient stereological method--the optical disector. The da...
Regional distribution of 5alpha-reductase type 1 and type 2 mRNA along the nonhuman primate (Macaca fascicularis) epididymis
Cynomolgus monkey RT-PCR gene expression
2009/2/17
The 5alpha-reduced metabolites of testosterone, including dihydrotestosterone, are considered the primary regulators of epididymal function. Two genes encode two 5alpha-reductase isozymes. We exam...
Progesterone-induced calcium influx in cynomolgus monkey（Macaca fascicularis）spermatozoa
Progesterone-induced calcium cynomolgus monkey spermatozoa
2008/12/25
For in vitro capacitation to occur in cynomolgus monkey (Macaca fascicularis) spermatozoa, there is an absolute requirement for exogenous stimulation with the sperm activators, caffeine (1 mM) and d...
Expression of Orphan Receptors TR2, TR3, TR4, and p53 in Heat-Treated Testis of Cynomolgus Monkeys（Macaca fascicularis）
Heat shock spermatogenesis primate
2008/12/24
To investigate the possible role of testicular orphan receptors (TR) TR2, TR3, and TR4 in the process of germ cell apoptosis in the heat-treated testis of monkey, we have examined the spatiotemporal...
Effects of Various Extenders and Permeating Cryoprotectants on Cryopreservation of Cynomolgus Monkey（Macaca fascicularis）Spermatozoa
Sperm freezing motility plasma membrane acrosome permeability coefficient
2008/12/23
The cryoprotective effects of 11 different extenders, TTE, DM, mDM, LG-DM, G-DM, TCG, TEST, TSM, Test-M, Test-H, and LM, on sperm cryopreservation of cynomolgus monkey (Macaca fascicularis) have bee...
Pharmacokinetics and Degree of Aromatization Rather Than Total Dose of Different Preparations Determine the Effects of Testosterone：A Nonhuman Primate Study in Macaca fascicularis
Spermatogenesis testis male contraception clinical chemistry primates
2008/12/19
Currently available testosterone (T) preparations differ substantially in their pharmacokinetic profile that might influence their androgenic properties in terms of suppression of the gonadal axis, ef...
Mild Testicular Hyperthermia Induces Profound Transitional Spermatogenic Suppression Through Increased Germ Cell Apoptosis in Adult Cynomolgus Monkeys (Macaca fascicularis)(
Azoospermia germ cell death heat primate spermatogenesis
2008/12/15
We have previously demonstrated that mild testicular hyperthermia induces stage-specific and germ cell—specific apoptosis in rat and mouse testes. The objectives of this pilot study were to examine wh...