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The antigonadotropic action of testosterone but not 7alpha-methyl-19-nortestosterone is attenuated through the 5alpha-reductase pathway in the castrated male rat pituitary gland
antigonadotropic action testosterone 7alpha-methyl-19-nortestosterone 5alpha-reductase castrated male rat pituitary gland
2008/12/25
The enzyme 5alpha-reductase plays a significant role in the prostate to amplify the action of testosterone (T) by converting it to a more potent androgen, dihydrotestosterone (DHT). The role of 5alp...