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How parathyroid hormone (PTH) increases bone mass is unclear, but understanding this phenomenon is significant to the improvement of osteoporosis therapy. Nmp4/CIZ is a nucleocytoplasmic shuttling tra...
Connexin (Cx) proteins are essential for cell differentiation, function and survival in all tissues with Cx43 being the most studied in bone. We now report that Cx37, another member of the connexin fa...
Breast cancer metastasis to bone triggers a vicious cycle of tumor growth linked to osteolysis. Breast cancer cells and osteoblasts express the epidermal growth factor receptor (EGFR) and produce ErbB...
The protein tyrosine kinase Pyk2 is highly expressed in osteoclasts, where it is primarily localized in podosomes. Deletion of Pyk2 in mice leads to mild osteopetrosis due to impairment in osteoclast ...
The aim of the present work was to evaluate the effect of a selective cyclooxygenase-2 (COX-2) inhibitor (meloxicam) on the alveolar bone loss progression in experimentally induced periodontitis. Fort...
Osteoporosis, a disease characterized by progressive bone loss, has been the target of several studies in the past few years. It results in a much higher risk for fractures and might cause slower bone...
Bisphosphonates are currently used in the treatment of many diseases involving increased bone resorption such as osteoporosis. Statins have been widely used for the treatment of hypercholesterolemia a...
The purpose of this study was to compare histologic and morphometric procedures of bone height measurement. Microscopic measurements are the most frequent methods in periodontal studies with animals, ...
The aim of the present study was to radiographically evaluate the effect of smoking on bone loss resulting from chronic periodontitis. Periapical radiographs were analyzed of 80 patients with chronic ...
Peri-implantitis is the inflammatory process that takes place around alveolar bone surrounding the dental implant. Unless treated, it may result with the loss of the implant. Another cause of the loss...
To clarify the changes of the mandible and alveolar bone in postmenopausal osteoporosis, we examined the changes of structure in mandible and alveolar bone of ovariectomized (OVX) rats. Twelve female ...
We studied bone formation induced by recombinant human bone morphogenetic protein-2 (rhBMP-2) combined with polylactate-polyglycolate-copolymer/gelatine sponge complexes (PGS) at palatal subperiosteal...
We previously reported the presence of type I, and III collagen (Col-I, III) and proliferating cells in human alveolar bone cells (HABCs) three-dimensional (3D) grafts (spheroid). The existence and d...
We studied the possibility of using grafts composed of human alveolar bone periosteal cells (HABPCs) for periodontal regeneration. HABPCs were inoculated four times to become a multilayer cell sheet e...
Recent studies have suggested that the use of platelet-rich plasma (PRP) combined with bone graft materials may be effective in the treatment of periodontal intrabony defects in humans. However, no cl...

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