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搜索结果: 1-15 共查到临床医学 Leukemia相关记录35条 . 查询时间(0.042 秒)
长期造血干细胞(long-term hematopoietic stem cell, LT-HSC)通过自我更新和多向分化维持机体的终身造血。在稳态下,这群稀有的成体干细胞通过保持静息状态以减少活性氧(ROS)的产生从而保证其基因组的稳定性。然而,当遭受造血压力刺激时,LT-HSC会退出静息状态并快速活化和增殖,从而导致细胞内的ROS水平迅速升高,进而产生无碱基位点(AP位点)等DNA氧化损伤。当...
近日,我校在读博士王莹、李护君,及朱峰副教授在CAR-T疗法的临床研究方面取得了新的进展,相关结果分别发表在血液学领域权威期刊《Leukemia》(JCR 1区 TOP期刊 IF:9.9)和《Bone Marrow Transplantation》(JCR 1区)。论文题目:Safety and efficacy of chimeric antigen receptor (CAR)-T-cell ...
天津医科大学内科学课件 Leukemia
Objective: To evaluate the efficacy of imatinib in chronic myeloid leukemia patients with variant translocations. Methods: Forty eight chronic myeloid leukemia patients carrying variant translocations...
西安交通大学医学院血液系统疾病课件 Leukemia
杨仁池、张磊课题组在Leukemia期刊发表文章“Analysis of calreticulin mutations in Chinese patients with essential thrombocythemia: clinical implications in diagnosis, prognosis and treatment”
PI3K in juvenile myelomonocytic leukemia     JMML  PI3K   PTPN11  Shp2  p110 delta       2015/5/21
Juvenile Myelomonocytic Leukemia (JMML) is rare, fatal myeloproliferative disease (MPD) affecting young children, and is characterized by expansion of monocyte lineage cells and hypersensitivity to Gr...
We report a 21-year-old woman who was admitted because of unilateral facial paresis and then developed progressive ascending flaccid tetraparesis with generalized areflexia. Electrodiagnostic studies ...
中国医学科学院实验血液学国家重点实验室王建祥课题组在在Leukemia期刊发表文章"PIG7, transactivated by AML1, promotes apoptosis and differentiation of leukemia cells with AML1-ETO fusion gene.”
Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy. Skeletal abnormalities have been described in association with ALL including osteoprosis and bone fractures. Different facto...
Background: Antiphospholipid antibodies, including lupus anticoagulants and anticardiolipin (aCL) antibodies are associated with a wide variety of disorders including malignancies. The aim of this stu...
A link between dermatomyositis and neoplasia has long been suspected. The precise incidence of this association remains controversial, owing to varying criteria used to diagnose dermatomyositis. Altho...
In this study, serum and fingernali Cu and Mg levels of 10 children with acute Iymphoblastic leukemia and 12 healthy children were determined. Copper and magnesium levels of the sera and supernatants...
Background: Over 50% of patients with AML still relapse after autologous stem cell transplantation. We investigated the efficacy and feasibility of a new conditioning regimen consisting of a moderate ...
Background: There is a risk of viral hepatitis for children with leukemia. Both hepatitis B and C virus infections cause major problems in the management of leukemic patients. In this study, we evalua...

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