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Alarming Dendritic Cells for Allergic Sensitization
alarmins asthma danger signals dendritic cells IL-1
2010/11/12
Allergic patients mount a Th2 response to common allergens, like house dust mite (HDM), pollens, molds and animal dander. Most inhaled antigens are immunologically inert, however if these antigens are...
Tolerance Induction by CD40 Silenced Dendritic Cells through Antisense
Dendritic cell Antisense CD40 Tolerance induction
2015/9/18
Background: One of the valuable tools for inhibiting the specific gene expression is antisense technique. To determine T cell responses, co-stimulatory molecule expression on the antigen presenting ce...
Dendritic cells (DC) play key rolls in various aspects of immunity. The functions of DC depend on the subsets as well as their location or activation status. Understanding developmental lineages, prec...
Dendritic Cells—Importance in Allergy—
asthma atopic dermatitis contact dermatitis Th1/Th2
2010/11/18
In this review we discuss the role of dendritic cells (DC) in the pathogenesis of allergic contact hypersensitivity (ACH) and atopic disorders, such as asthma and atopic eczema. In ACH patients, DC re...
Dendritic Cells—A Conductor of T Cell Differentiation—
dendritic cells regulatory T cells Th1 Th2 Th17
2010/11/18
Induction of different types of adaptive immune responses depending on the nature of antigens and the environmental context is crucial to cope with a variety of pathogens and concurrently to avoid pat...
Dendritic Cells-Nature and Classification
Dendritic cells Development Functional plasticity Immune response Lineage Subset heterogeneity
2010/11/18
Dendritic cells (DCs) are antigen (Ag)-presenting cells (APCs) characterized by a unique capacity to stimulate naïve T cells and initiate primary immune responses. Recent studies suggest that DCs...
High Production of IL-18 by Dendritic Cells Induced by Sera from Patients with Primary Antibody Deficiency
Common variable immunodeficiency Interleukin-18 X-linked agammaglobulinemia
2010/4/8
Predominantly antibody deficiencies are a category of primary immunodeficiency diseases, which
consist of several rare disorders such as common variable immunodeficiency (CVID) and X-linked agammaglo...
Dendritic Cells Bearing HLA-G Inhibit T-Cell Activation in Type 1 Diabetes
Dendritic cell HLA-G IFN-β (Interferon β)
2010/4/2
HLA-G is normally expressed on human trophoblast cells. It is a non-classical MHC molecule class I b. The role of HLA-G in diabetic type 1 is not known.We investigated the role of IFN-β in induction H...