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Co-administration of Grape Seed Extract and Exercise Training Improves Endothelial Dysfunction of Coronary Vascular Bed of STZ-Induced Diabetic Rats
Diabetic Vascular Complication Grape Seed Extract Exercise Coronary Vessels
2015/10/9
Background: One of the known complications of diabetes mellitus is vascular dysfunction. Inability of the coronary vascular response to cardiac hyperactivity might cause a higher incidence of ischemic...
STUDY OF CORRELATION BETWEEN SYSTOLIC BLOOD PRESSURE AND ANGIOTENSIN CONVERTING ENZYME (ACE) ACTIVITY IN STZ INDUCED DIABETIC RATS
STZ induced diabetic rats Diabetes mellitus morbidity mortality
2010/1/6
Background: Diabetes mellitus is a worldwide health problem affecting 1-2% of the population. It is responsible for numerous morbidity and mortality consequences due to vascular events such as hyperte...
STZ诱导的糖尿病大鼠急性心肌梗死后心脏重构及相关基因的表达
糖尿病 心肌梗死 左室重构 微序列分析
2010/4/22
目的： 研究糖尿病大鼠急性心肌梗死的心肌重构及相关基因的表达。方法：糖尿病诱导10周，未作任何治疗，结扎左前降支，透射电子显微镜检查、超声心动描记术、心脏重量与胫骨长度比、组织学变化、基因芯片、实时-PCR用于监测直至56 d的变化。结果：结扎后，糖尿病大鼠生存率显著低于非糖尿病大鼠。病理生理学变化表明DM能够加速梗死后心肌重构。根据筛选条件，选择164个与心脏重构相关的基因，例如富含亮氨酸的PP...