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Identification of a potential FSH modulatory protein in human testis and seminal plasma
potential FSH modulatory protein human testis seminal plasma
2009/2/23
A variety of factors capable of inhibiting the in vitro binding of FSH to its receptor have been identified in gonadal tissues from males and females. Interest in these factors has been stimulated b...
Steroid metabolism and morphologic features of the human testis
Steroid metabolism morphologic features human testis
2009/2/23
Serum FSH, LH, and testosterone were studied in 114 infertile men with poor sperm production. Testicular biopsies were taken and classified morphologically. In 90 specimens, the pattern of convers...
Immunohistochemical localization of beta-endorphin in hyperplastic interstitial tissue of the human testis
/3-endorphin Leydig cells immunohistochemistry
2009/2/23
The immunohistochemical localization of beta-endorphin in the normal testis (two patients) and in the pathologic testis (two cases of Sertoli Cell Only Syndrome, two cases of Klinefelter Syndrome,...
Evidence for catecholaminergic, neuronlike cells in the adult human testis：changes associated with testicular pathologies
catecholaminergic neuronlike cells adult human testis
2009/2/18
Neuronlike, catecholaminergic cells expressing tyrosine-hydroxylase (TH) have recently been found in the testis of a nonhuman primate species, the rhesus monkey. We examined whether neuronlike cel...
We have previously found the presence of endothelin (ET) receptor and ET-like immunoreactivity in rat testis. We now extend our studies from rat to human testis. We found expression of a specific tr...
Motile sperm in human testis biopsy specimens
Wet prep motility reproductive tract obstruction
2009/2/12
We prospectively studied 62 consecutive infertile men who underwent 100 intraoperative wet prep cytological examinations of testis biopsy material obtained simultaneously with permanently fixed spec...
Ontogeny of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase（3 beta-HSD）in human testis as studied by immunocytochemistry
Ontogeny 3ı -hydroxysteroid dehydrogenase/iı -iS.” isomerase human testis immunocytochemistry
2009/2/7
The enzyme complex 3 beta-hydroxy-5-ene-steroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD) is involved in the biosynthesis of all classes of active steroids, including androgens. To correl...
Assessment of the androgen environment within the human testis：minimally invasive method to obtain intratesticular fluid
Testosterone spermatogenesis ABP
2008/12/29
Previous studies of the rat have shown that testosterone concentrations within the interstitial and seminiferous tubularfluids of the testes are significantly higher than normal serum levels, and furt...
Transmembrane versus soluble stem cell factor expression in human testis
Transmembrane soluble stem cell human testis
2008/12/25
The interaction between stem cell factor (SCF), a ligand produced by Sertoli cells, and its c-kit receptor on germ cells is necessary for successful spermatogenesis in animal models. SCF can be alte...
Expression and Possible Functions of a Novel Gene SPATA12 in Human Testis
Germ cell specific stage specific spermatogenesis
2008/12/24
In our previous study, a novel human testis-specific gene, SPATA12, was identified using the digital differential display program. In the current study, both SPATA12 mRNA and protein levels in...
Ghrelin Expression in Human Testis and Serum Testosterone Level
Ghrelin Expression Human Testis Serum Testosterone
2008/12/24
Ghrelin, which is the endogenous ligand for the growth hormone (GH) secretagogue receptor (GHS-R), has been primarily linked to the central neuroendocrine regulation of GH secretion and food i...
Novel Development-Related Alternative Splices in Human Testis Identified by cDNA Microarrays
Alternative splicing spermatogenesis regulatory mechanism protein diversity spliceoforms
2008/12/23
Alternative splicing of premessenger RNA is an important regulatory mechanism that increases the diversity of proteins transcribed from a single gene. This is particularly important in the testis be...
Evidence for the Presence of Angiogenin in Human Testis
Immunohistochemistry in situ hybridization
2008/12/22
We have reported the expression and possible roles of angiogenin, a potent angiogenic factor, in human female reproductive organs. In this study, we investigated the expression of angiogenin in the ...
Expression of a Novel RAD23B mRNA Splice Variant in the Human Testis
RAD23 alternative splice ubiquitin spermatogenesis proteolysis self-balance
2008/12/22
A gene coding a novel human RAD23B protein named RAD23-like protein B, presumably involved in spermatogenesis, was identified and characterized using a complementary DNA (cDNA) microarray. In the hu...