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Princeton University researchers have found that dopamine – a brain chemical involved in learning, motivation and many other functions – also has a direct role in representing or encoding movemen...
Drug addiction is a behavioral disorder characterized by impulsive behavior and continued intake of drug in the face of adverse consequences. Millions of people suffer the financial and social consequ...
The etiology of many neurodegenerative diseases is unknown, but a number of studies indicate that a combination of both genetic and environmental factors contribute to the progression of disease. Expo...
Alcohol and cocaine are commonly co-abused drugs, and those meeting criteria for both cocaine and alcohol use disorders experience more severe behavioral and health consequences than those with a sing...
Dopamine cell bodies in the substantia nigra of the midbrain and with their terminals projecting to the neostriatum form the nigrostriatum and these dopamine neurons degenerate in Parkinson’s disease ...
Gold nanotadpoles were synthesized by a simple temperature-reducing seeding approach. A novel gold electrode modified with gold nanotadpoles through a sulphydryl-terminated self-assembled monolayer ...
The antagonistic effects of helium pressure and certain inhalation anesthetics on the dopamine-sensitive cAMP response in the caudate nucleus of rat brain were examined. Helium pressure suppressed bas...
Adverse neurological manifestations of exposure to high hydrostatic pressure include tremor and convulsions, suggesting an alteration in synaptic transmission, particularly with inhibitory pathways. B...
Endogenous dopamine (DA) and 3,4-dihydroxyphenylacetic acid (DOPAC) were measured by high performance liquid chromatography with electrochemical detection in perfusate from continuously superfused rat...
Exposure to environmental pressures in excess of 20 atm abs can precipitate a hyperexcitability state known as high pressure neurologic syndrome (HPNS). Little is known about the underlying neurochemi...
The protective roles of low-dose dopamine and mannitol infusion in the renal function of patients undergoing cardiovascular surgery were compared in 36 patients by measuring urine N-acetyl-b-D- glucos...
Hyperbaric nitrogen-oxygen exposure developed in rats a decrement of the striatal dopamine release, which was reversed by repetitive exposures. This dopamine decrease could be the result of the antago...
The aim of this study is to determine whether pramipexole hydrochloride hydrate (PHH) and atropine sulfate affect valproic acid (VPA) pharmacokinetics and to evaluate how plasma VPA concentrations a...
Endogenous dopamine (DA) and 3,4-dihydroxyphenylacetic acid (DOPAC) were measured by high performance liquid chromatography with electrochemical detection in perfusate from continuously superfused rat...
Oseltamivir (Tamiflu®, Roche Laboratories, Inc.) is a neuraminidase inhibitor that can cause jumpdown behaviors in children. There is a mouse slip-down model, in which the dopamine D2 receptor a...

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