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Prostaglandin dehydrogenase activity of rat and rabbit testicular tissues and accessory glands before and after castration
Prostaglandin dehydrogenase activity rat rabbit testicular tissues
2009/2/20
Rat reproductive tissues contained both 15-hydroxy-prostaglandin dehydrogenase (PGDH) and delta 13-reductase activities, while rabbit tissues exhibited only PGDH activity. In the rat, delta 13-reduc...
Effect of Castration and Androgen Treatment on Sex-Linked Reactivity of Rat Aorta to a Thromboxane-Mimic
castration androgen-treatment vascular reactivity thromboxane-mimic
2009/2/19
In order to examine the possible role of androgens in the isotonic response of the isolated rat aorta, a highly active mimic of thromboxane was employed. The maximum response to this TXA2-mimic U4...
Disappearance of Inhibin-like Activity in Bull Seminal Plasma Following Castration
inhibin seminal plasma castration
2009/2/19
Ejaculates from normal and castrated bulls were evaluated for the presence of inhibin-like activity. Inhibin activity found in the seminal plasma of normal bulls became undetectable after castrati...
The influence of castration on pharmacologically induced penile erection in the cat
Testosterone vasoactive agents cAMP cGMP
2009/2/18
The purpose of this study was to investigate the in vivo effects of intracavernosal injections of adrenomedullin (ADM), calcitonin gene-related peptide (CGRP), nociceptin, vasoactive intestinal po...
Thanatogen expression during involution of the rat ventral prostate after castration
Apoptosis TRPM-2 clusterin transglutaminase poly(ADP)ribose polymerase
2009/2/12
After castration the rat ventral prostate undergoes regression. This process occurs due to the induction of apoptosis, or active cell death, in the epithelial cells of the gland. Several genes, incl...
Effects of castration and recombinant human inhibin administration on circulating levels of inhibin and gonadotropins in adult male monkeys
castration recombinant human inhibin administration circulating levels inhibin gonadotropins adult male monkeys
2009/2/12
Inhibin has been suggested to play a role in gonadal feedback regulation of follicle-stimulating hormone (FSH) secretion; however, neither the half-life nor the time course of action of recombinan...
An investigation of the requirement for increased LH secretion during the compensatory response in androgen secretion after unilateral castration of the adult rat
Hormone implants immunoactive bioactive
2009/2/10
The endocrine mechanisms underlying the response to unilateral castration were examined by determining systemic androgen and luteinizing hormone (LH) concentrations, as well as testicular vein andro...
Changes in Testosterone and Dihydrotestosterone Levels in Male Rat Accessory Sex Organs, Serum, and Seminal Fluid After Castration:Establishment of a New Highly Sensitive Simultaneous Androgen Measurement Method
LC-MS/MS hormone prostate seminal vesicles
2008/12/23
It is known that abnormal androgen dynamics in the tissues is a cause of androgen-dependent disorders. Investigation of tissue androgen levels could provide a clue to the elucidation of disorders....
Medical Castration With LHRH Agonists:25 Years Later With Major Benefits Achieved on Survival in Prostate Cancer
Medical Castration With LHRH Agonists Major Benefits Achieved Survival Prostate Cancer
2008/12/22
Prostate cancer is the most frequently diagnosed cancer and the second cause of cancer death in men in North America (Jemal et al, 2003). In fact, one of eight men will be diagnosed with prostate canc...
Effects of Medical or Surgical Castration on Erectile Function in an Animal Model
Androgens trabecular smooth muscle corpus cavernosum veno-occlusion vardenafil leuprolide acetate
2008/12/19
The goal of this study was to investigate the effects of medical castration (luteinizing hormone-receptor hormone [LH-RH] agonist treatment) or surgical castration on erectile function in an animal ...