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Structural basis for RNA replication by the SARS-CoV-2 polymerase
2019-nCoV SARS-CoV-2 COVID-19 remdesivir favipiravir polymerase RdRP virus nsp12 nsp8
2020/6/11
Nucleotide analog inhibitors, including broad-spectrum remdesivir and favipiravir, have shown promise in in vitro assays and some clinical studies for COVID-19 treatment, this despite an incomplete me...
Simultaneous and Rapid Detection of Salmonella typhi, Bacillus anthracis, and Yersinia pestis by Using Multiplex Polymerase Chain Reaction (PCR)
Salmonella typhi Bacillus anthracis Yersinia pestis Multiplex PCR
2015/10/9
Background: Salmonella typhi, Bacillus anthracis, and Yersinia pestis are some serious human pathogens, which their early diagnosis is of great importance. Salmonella typhi, Bacillus anthracis, and Ye...
Investigation of Subgingival Profile of Periodontopathic Bacteria Using Polymerase Chain Reaction
Periodontopathic bacteria Polymicrobial infection
2010/12/1
Periodontopathic bacteria such as Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Tannerella forsythia, Campylobacter rectus and Treponema denticola play an important role in the init...
Analysis of the presence of pathogens which predict the risk of disease at peri-implant sites through polymerase chain reaction (PCR)
Actinobacillus actinomycetemcomitans Porphyromonas gingivalis Prevotella intermedia PCR
2009/10/19
The presence of DNA of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, and Prevotella intermedia in the peri-implant sulcus samples of 19 partially edentulous patients was analyzed by ...
Analysis of ras Gene Mutation in Human Oral Tumours by Polymerase Chain Reaction and Direct Sequencing
Oral tumour PCR Direct sequencing Tobacco-specific nitrosamines
2009/6/29
Genetic alterations in proto-oncogenes or tumour suppressor genes are believed to be one of the key events in the multistage process of carcinogenesis. Activating point mutations occurring in either o...
Detection of Human Papillomavirus Infection in Esophageal Carcinomas by the Histopathological Method and Polymerase Chain Reaction Technique
Esophagus cancer Human Papillomavirus
2009/6/26
A series of 30 surgical resection materials of patients with squamous cell carcinoma (SCC) and 10 with adenocarcinoma (AC) were analyzed histologically and by polymerase chain reaction (PCR) to demons...
Typing of Methicillin-Resistant Staphylococcus aureus by Ribosome Spacer and Arbitrarily Primed Polymerase Chain Reaction
Staphylococcus aureus epidemiology polymerase chain reaction
2009/6/23
Thirty-five methicillin-resistant Staphylococcus aureus (MRSA) clinical isolates were collected from 3 hospitals in the northern and southern parts of Palestine between February and May 1998. These is...
The efficacy of quantitative fluorescent-polymerase chain reaction (QF-PCR) in the diagnosis of prenatal aneuploidy
Aneuploidy QF-PCR conventional karyotype analysis
2010/1/11
Aim: To investigate the efficacy of quantitative fluorescent-polymerase chain reaction (QF-PCR) in the diagnosis of aneuploidy. Materials and methods: The study included 40 pregnant women considered t...
P450 aromatase messenger ribonucleic acid expression in male rat germ cells: detection by reverse transcription-polymerase chain reaction amplification
Germ cells spermatids P450 aromatase estrogen
2009/2/17
We have previously demonstrated that cytochrome P450 aromatase (P450arom) protein, an estrogen-synthesizing enzyme, is present and active in germ cells of the adult mouse testis. To establish that P...
Viability of the Cariostat® medium as a source of DNA for further analysis through polymerase chain reaction
Cariostat DNA Streptococcus mutans PCR
2008/4/16
This simulation study was carried out to analyze and evaluate Cariostat-inoculated samples through a conventional PCR protocol specific for Streptococcus mutans strains and also for the purpose of est...
Detection of Chlamydia trachomatis in endocervical specimens by an enzyme-linked polymerase chain reaction assay
Chlamydia trachomatis PCR-EIA Cervicitis Sexually Transmitted Infections
2010/4/9
Chlamydia trachomatis (CT) is the most common cause of sexually transmitted infections (STI) worldwide and its early detection and treatment can reduces the high morbidity associated with this infecti...
Detection of Chlamydia trachomatis in endocervical specimens by an enzyme-linked polymerase chain reaction assay
Chlamydia trachomatis PCR-EIA Cervicitis Sexually Transmitted Infections
2010/4/9
Chlamydia trachomatis (CT) is the most common cause of sexually transmitted infections (STI) worldwide and its early detection and treatment can reduces the high morbidity associated with this infecti...
DETECTION OF HUMAN PAPILLOMAVIRUS DNA SEQUENCES IN ORAL LESIONS USING POLYMERASE CHAIN REACTION
Oral squamous cell carcinoma Leukoplakia Lichen planus Human papillomavirus Polymerase chain reaction
2010/4/20
The purpose of the present study was to estimate the frequency of HPV DNA in four groups of oral lesions, including oral squamous cell carcinoma. Sixty paraffin-embedded oral tissue samples were exami...