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One of the challenges to working with canines is that whereas humans are primarily vocal communicators, canines are primarily postural and behavioral communicators. It can take years to gain some leve...
Mandibular necrosis in beagle dogs treated with bisphosphonates
osteonecrosis bisphosphonates
2014/12/4
Objectives – To test the effect of bisphosphonate (BP) treatment for up to 3 years on bone necrosis and osteocyte death in the mandible using a canine model. Materials and Methods –...
Mandible matrix necrosis in beagle dogs After 3-years of daily oral bisphosphonate treatment
osteonecrosis of the jaw remodeling suppression
2014/12/4
Purpose An increasing number of reports have implicated bisphosphonates as contributing to osteonecrosis of the jaw. The goal of this study was to evaluate mandible necrosis in beagle dogs treated for...
Alendronate reduces bone toughness of ribs without significantly increasing microdamage accumulation in dogs following three years of daily treatment
Bisphosphonates remodeling suppression
2014/12/4
Reduced bone toughness, the energy absorption capacity of the tissue, has been consistently documented in vertebrae of animals treated with a wide range of bisphosphonate doses. Data regarding toughne...
Compromised Osseous Healing of Dental Extraction Sites in Zoledronic Acid-Treated Dogs
bisphosphonates osseous healing
2014/12/4
Summary The goal of this study was to document how treatment with high doses of zoledronic acid affects dental extraction healing. Our results, showing significantly compromised osseous healing within...
Morphological Assessment of Basic Multicellular Unit Resorption Parameters in Dogs Shows Additional Mechanisms of Bisphosphonate Effects on Bone
basic multicellular unit alendronate
2014/12/4
Bisphosphonates (BPs) slow bone loss by reducing initiation of new basic multicellular units (BMUs). Whether or not BPs simply prevent osteoclasts from initiating new BMUs that resorb bone or also red...
In vivo reference point indentation reveals positive effects of raloxifene on mechanical properties following six months of treatment in skeletally mature beagle dogs
bone remodeling bone mechanics osteoporosis treatments indentation
2014/12/4
Raloxifene treatment has been shown previously to positively affect bone mechanical properties following one year of treatment in skeletally mature dogs. Reference point indentation (RPI) can be used ...
In vivo reference point indentation reveals positive effects of raloxifene on mechanical properties following six months of treatment in skeletally mature beagle dogs
bone remodeling bone mechanics osteoporosis treatments indentation
2014/11/6
Raloxifene treatment has been shown previously to positively affect bone mechanical properties following one year of treatment in skeletally mature dogs. Reference point indentation (RPI) can be used ...
Evaluation of Effects of Intraperitoneal CO2 Pressure in Laparoscopic Operations on Kidney,Pancreas,Liver and Spleen in Dogs
Laparoscopy Pneumoperitoneum Kidney Liver Pancreas Spleen
2015/10/8
Background: During laparoscopy, insufflation of an inert gas in the peritoneal cavity creates a working space to facilitate surgery. The space should be large enough to facilitate surgery without incr...
Prevalence of Giardia duodenalis among dogs seized by the Center for Control of Zoonoses (CCZ) of the city of Lages, Santa Catarina, Brazil
Giardia Duodenalis Dogs Zoonoses Brazil
2013/1/29
The knowledge of the epidemiology of parasitic infections in stray and domestic animals, especially of its incidence and prevalence, is fundamental to adopting effective prophylactic measures. Stray d...
Sensitivity and Specificity Determinations with Isoelectric Focusing Fractions of Blastomyces dermatitidis for Antibody Detection in Serum Specimens from Infected Dogs
Isoelectric Focusing ELISA Blastomycosis Lysate Antigen Antibody Detection
2013/2/19
Blastomycosis and histoplasmosis manifest as lung and systemic fungal infections in mammals caused by Histoplasma capsulatum, and Blastomyces dermatitidis. These infections exhibit cross reactivity of...
Spontaneous Mammary Carcinomas in Female Dogs: Association between Immunohistochemical Degrees of Neoplasia Aggressiveness and Residual Pyrethroids
Mammary Tumors Pyrethroids Carcinogenesis Neoplasia Aggressiveness
2013/2/19
Of the tumors diagnosed in the female dogs have the highest mammary neoplasias incidence. These neoplasias can be influenced by environmental contaminants. Despite evidence of pyrethroid toxicity, car...
Immunohistochemical Evaluation of Vascular Endothelial Growth Factor (VEGF) in Splenic Hemangiomas and Hemangiosarcomas in Dogs
Canine Spleen Angiogenesis Hemangiosarcoma Immunohistochemistry
2013/2/19
Formation of new blood vessels is paramount for tumour growth and metastatic dissemination and vascular endothelial growth factor (VEGF) is one of the key regulators of this process. The purpose of th...
Canine Prostate Carcinoma: Four Clinical Cases in Sexually Intact and Neutered Dogs
Prostate Carcinoma Neutered Dog
2013/2/19
Prostate cancer is one of the most important malignancies in men. In old men the frequency of prostate cancer at necroscopy has been reported to exceed 40%. Dogs are the only large mammals other than ...
Cross Infection of Strongyloides between Humans and Dogs in the Amami Islands, Japan
Strongyloides larvae cross infection
2010/12/10
Human strongyloidiasis is a parasitic infection induced by the nematode Strongyloides stercoralis which can cause gastrointestinal disturbances. It is believed to be a zoonosis with a potential for c...