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Alterations in human milk leptin and insulin are associated with early changes in the infant intestinal microbiome
milk leptin insulin the infant intestinal microbiome
2018/11/12
We read with great interest the study by Lemas et al. (1) that reported early changes in the gut microbiota composition and functions of exclusively breastfed infants born from obese mothers compared ...
Missense mutations in exon 2 of the porcine leptin receptor gene and their associations with litter size and body weight
LEPR SNPs pigs
2015/6/8
Leptin receptor (LEPR) gene is regarded as a “candidate-gene” of production traits. The aims of this study were to detect polymorphisms of exon 2 within LEPR gene and to investigate their associations...
Dexamethasone and Acetate Modulate Cytoplasmic Leptin in Bovine Preadipocytes
Acetate, Bovine, Cytoplasm, Dexamethasone, Leptin, Preadipocyte
2016/5/16
Hormonal and nutrient signals regulate leptin synthesis and secretion. In rodents, leptin is stored in cytosolic pools of adipocytes. However, not much information is available regarding the regulatio...
The Expression of Leptin, Estrogen Receptors, and Vitellogenin mRNAs in Migrating Female Chum Salmon, Oncorhynchus keta: The Effects of Hypo-osmotic Environmental Changes
Chum Salmon Estrogen Receptors Leptin Maturation Salinity Change Vitellogenin
2016/5/16
Leptin plays an important role in energy homeostasis and reproductive function in fish, especially in reproduction. Migrating fish, such as salmonoids, are affected by external environmental factors, ...
瘦蛋白(Leptin)自然选择和适应性进化研究概述
自然选择 适应性进化 瘦素蛋白基因 瘦素蛋白基因受体
2013/8/8
瘦素蛋白(leptin)是一种由脂肪组织分泌的激素, 在调节食欲、能量消耗以及控制体重方面发挥重要作用. 因为瘦素蛋白与肥胖相关, 所以瘦素蛋白基因(leptin)的研究对公共卫生和药物干预治疗肥胖有着重要意义. 由于其功能上的重要性, leptin基因通常高度保守. 但是, 一些研究在个别哺乳动物中检测到了快速进化和正选择作用, 提示这些物种的leptin的功能可能在它们适应环境的过程中发生了适...
中国金丝猴物种瘦素基因(Leptin)分子进化研究
瘦素基因 金丝猴 高海拔 适应
2013/9/6
灵长目疣猴亚科金丝猴属(Rhinopithecus)包括4个种, 即滇金丝猴(R. bieti)、黔金丝猴(R. brelichi)、川金丝猴(R. roxellana)和越南金丝猴(R. avunculus). 除越南金丝猴外, 其他3个种都分布于中国地区6大主要山脉的高海拔地区(>2000 m), 是目前已知栖息地海拔分布最高的非人类灵长类动物. 与其他疣猴亚科相比, 中国金丝猴物种有更好的适...
Effect of Permanent Hypoinsulinemia on Appetite, Performance, Carcass Composition, Blood Metabolites and Leptin Concentrations in Lambs
Hypoinsulinemia Leptin Appetite Performance Carcass Lamb
2016/4/29
Insulin has crucial roles in energy metabolism in all mammals but has been less studied in ruminants. An experiment was conducted to investigate the effects of hypoinsulinemia induction on appetite, p...
SNP Discovery in the Leptin Promoter Gene and Association with Meat Quality and Carcass Traits in Korean Cattle
Leptin Promoter SNP Identification Meat Quality Korean Cattle
2016/4/28
Leptin, the hormone product of the obese gene, is secreted predominately from white adipose tissue and regulates feed intake, energy metabolism and body composition. It has been considered a candidate...
Development of Bovine Specific Leptin Radioimmunoassay and Relationship of Plasma Leptin with Vitamin A and Age of Wagyu
Bovine Fattening Leptin RIA Vitamin A Wagyu
2016/4/28
Leptin is produced by adipocytes and its role in the regulation of lipid metabolism, feed intake, productive and reproductive performance of domestic animal species has been greatly stressed and exten...
The Body Weight-related Differences of Leptin and Neuropeptide Y (NPY) Gene Expression in Pigs
Fat Deposition Gene Expression Leptin Neuropeptide Y Pig
2016/4/27
To determine if body weight change is directly related to altered leptin and neuropeptide Y (NPY) gene expression, we assessed adipose tissue weight, percent body fat, leptin and NPY mRNA levels and s...
摘要利用PCR-SSCP技术研究了南阳牛、秦川牛、郏县红牛、西镇牛、鲁西牛和荷斯坦奶牛6个牛品种539个个体leptin基因的遗传多态性。结果表明, PCR扩增产物大小为330 bp, PCR-SSCP分析表现出多态。南阳牛、秦川牛、郏县红牛、西镇牛、鲁西牛和荷斯坦奶牛的A等位基因频率分别为0.558，0.492，0.571，0.658，0.591，0.615；B等位基因频率分别为0.442，0....
人Leptin的基因克隆及其在大肠杆菌中的表达
Leptin 克隆和序列分析 表达 大肠杆菌
2007/12/24
摘要 用 RT- PCR自脂肪细胞 RNA扩增人瘦素 (leptin)基因的 c DNA片段 (约 50 0 bp)并克隆至克隆载体 p SK(+) ,获得重组质粒 p SK- OB,DNA序列分析显示获得的 Leptin基因和文献报道一致 .用限制酶 Eco R 和 Bam H 从 p SK- OB切下并插入原核表达载体 p BV2 2 0的相应限制酶位点 ,转化大肠杆菌 DH5α.转化菌株经 ...
Leptin对GH3细胞GH分泌的影响及与第二信使的关系.
2007/7/28
专著信息
书名
Leptin对GH3细胞GH分泌的影响及与第二信使的关系.
语种
中文
撰写或编译
作者
刘亚莉,钟延清,迟素敏
第一作者单位
出版社
生理学报（待发表）
出版地
出版日期
年
月
日
标准书号
介质类型
页数
字数
开本
相关项目
Leptin对生长激素细胞GH分泌的调控及其机制
期刊信息
篇名
Leptin受体三种亚型在大鼠垂体前叶的表达及Leptin对大鼠生长激素细胞胞内游离钙的影响.
语种
中文
撰写或编译
作者
刘亚莉,钟延清,朱运龙,迟素敏
第一作者单位
刊物名称
中国应用生理学杂志
页面
2004；20(4)：349-353
出版日期
2004年
月
日
文章标识(ISSN)
相关项目
Leptin对生长激素细胞GH分泌的调控及其机制
Association of SNP Marker in the Leptin Gene with Carcass and Meat Quality Traits in Korean Cattle
Leptin Gene SNP Marker Carcass and Meat Quality Traits Korean Cattle
2016/4/25
Leptin is the hormone product of the obese gene and is synthesized and secreted predominantly by white adipocytes and relates to the feedback system that regulates long-term body fat weight and compos...