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Innate defense capability of challenged primary bovine mammary epithelial cells after an induced negative energy balance in vivo
pbMEC mastitis energy deficit E. coli
2015/6/23
Negative energy balance (NEB), if followed by metabolic imbalance, is a common problem in
high-yielding dairy cows frequently associated with inflammation of the mammary gland. After entering the
...
Use of computer image analysis for in vivo estimates of the carcass quality of bulls
cattle carcass quality computer image analysis Slovak Pied breed
2015/6/4
The aims of the paper were to construct models for the estimation of carcass quality by means of computer image analysis and to verify computer photometry as an in vivo method of carcass quality predi...
In Vivo Analysis of Human LHX3 Gene Regulation
Gene Regulation Pituitary Combined Pituitary Hormone Deficiency LHX3
2015/5/25
LHX3 is a transcription factor important in pituitary and nervous system development. Patients with mutations in coding regions of the gene have combined pituitary hormone deficiency (CPHD) that cause...
The LHX3 transcription factor is essential for pituitary gland and nervous system development in mammals. In humans, mutations in the LHX3 gene underlie combined pituitary hormone deficiency (CPHD) di...
Molecular “hats” allow in vivo activation of disguised signaling peptides
Molecular hats vivo activation disguised signaling peptides
2014/12/30
When someone you know is wearing an unfamiliar hat, you might not recognize them. Georgia Institute of Technology researchers are using just such a disguise to sneak biomaterials containing peptide si...
In Vivo Investigations of Polymer Conjugates as Therapeutics
polymer in vivo breast cancer
2014/12/12
Polymer conjugates offer a way to introduce materials into the body that would normally be rejected or cause toxicity. Two polymers are investigated in vivo for uses in chemotherapeutic delivery, prot...
During mitosis, replicated chromosomes are equally distributed among two daughter cells by means of a multi-component machine called the mitotic spindle. Spindle formation and function has been shown ...
In Vivo Labeling Of A Model β-Clam Protein With A Fluorescent Amino Acid
nonsense suppression technique L-(7-hydroxycoumarin-4-yl) ethyl glycine unnatural amino acid CRABP I
2014/12/12
Proteins can be labeled with different tags to enable their structural and functional investigations. In addition, labeling proteins at specific sites helps in studying the conformational dynamics of ...
Characterization of yeast U14 snoRNA interactions required for rRNA processing, and development of a novel in vivo rDNA system for dissecting ribosome biogenesis
U14 small nucleoli ribosomal RNA DNA bases yeast elements
2014/12/11
U14 small nucleolar RNA (snoRNA) is required for processing of 18S ribosomal RNA. It was hypothesized that U14 might base pair with 18S RNA through two highly conserved U14 sequence elements known as ...
Box C/D small nucleolar RNAs: Biogenesis, structure and utilization for in vivo ribozyme studies
Eukaryotic cells biological origin yeast capsule
2014/12/11
Eukaryotic cells contain scores of small nucleolar RNAs (snoRNAs), which are required for maturation of pre-rRNA. Two large snoRNA families exist defined by vital box C/D and box H/ACA motifs. The goa...
A new strategy for RNA structure probing in vivo: Targeting methylation small nucleolar RNPs to new sites in ribosomal RNA
Eukaryotic ribosomal RNA nucleotide RNA proteins DNA methylation
2014/12/11
Eukaryotic ribosomal RNAs (rRNAs) contain scores of 2′-O-methylated nucleotides that are formed by a large family of small RNA:protein machines called snoRNPs. The snoRNPs contain a small nucleolar RN...
The effects of polychlorinated biphenyls on thyroid hormone-mediated action in vivo and in vitro
Polychlorinated biphenyls (PCBS) environmental pollutants polychlorinated biphenyls (PCBS) nerve defect thyroid hormone thyroid hormone
2014/12/11
Polychlorinated biphenyls (PCBs) are ubiquitous environmental contaminants routinely found in human and animal tissues. Developmental exposure to PCBs is associated with neuropsychological deficits, w...
Molecular mechanisms through which 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) interferes with estrogen regulation of PRL gene expression in vivo and in vitro
Aromatic hydrocarbon environmental pollution chemicals adipose tissue plasma gland hormone
2014/12/11
Polyhalogenated aromatic hydrocarbon (PHAH) belongs to a group of ubiquitous environmental contaminants. Among them, 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD) is one of the most toxic synthetic chem...
Exploring dimethylsulfate for in vivo proteome footprinting
Exploring dimethylsulfate proteome footprinting
2011/1/5
Protein footprinting is a new methodology that is based on probing, typically with the use of mass spectrometry, of reactivity of different aminoacid residues to a modifying reagent. Data thus obtaine...
Dynamics of Bacteriophage Genome Ejection In Vitro and In Vivo
Dynamics Bacteriophage Genome Ejection Vitro Vivo
2011/1/5
Bacteriophages, phages for short, are viruses of bacteria. The majority of phages contain a double-stranded DNA genome packaged in a capsid at a density of ~500 mg/ml. This high density requires subst...